Birefringence-derived artifact in optical coherence tomography imaging of the lamina cribrosa in eyes with glaucoma

Birefringence-derived artifact in optical coherence tomography imaging of the lamina cribrosa in eyes with glaucoma

Blog Article

Abstract We investigated birefringence-derived artifacts that potentially mimic focal defects of the lamina cribrosa (focal LC defects) in optical coherence tomography (OCT) jacques marie mage baudelaire 2 imaging of eyes with glaucoma.This study included 74 eyes of 48 patients with glaucoma.Five horizontal line B-scan images of the optic disc were obtained using commercial swept-source OCT.From a dataset of prototype swept-source polarization-diversity OCT, we calculated the following types of OCT images: polarization-dependent, polarization-dependent attenuation-coefficient, polarization-independent, and polarization-independent attenuation-coefficient.

We assessed the commercial OCT images for the presence of birefringence-derived artifacts by comparison with the polarization-diversity OCT images.Commercial OCT showed suggestive findings of focal LC defects in 17 of 74 eyes.Reevaluation using polarization-independent OCT revealed that the focal LC defects in one of 17 eyes (5.9%) were actually birefringence-derived artifacts.

This study demonstrated the existence of birefringence-derived artifacts mimicking focal LC defects in commercial OCT imaging and indicated that polarization-diversity OCT is revolution de la fleur an effective tool to evaluate the presence of these artifacts.